Description
Mouse BTLA Recombinant Protein (mFc Tag)
| Description: | Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:12796776, PubMed:14652006). May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14 (PubMed:19915044). In cis interactions, appears to play an immune regulatory role inhibiting in trans interactions in naive T cells to maintain a resting state. In trans interactions, can predominate during adaptive immune response to provide survival signals to effector T cells (PubMed:19915044). |
| Product name: | Mouse BTLA Recombinant Protein (mFc Tag) |
| Synonyms: | BTLA,CD272 |
| Type: | protein |
| Size: | 50 µg |
| Name: | Mouse BTLA |
| Origin: | Mouse |
| Source: | HEK293 |
| Protein Type: | Recombinant |
| Application: | Contact Technical Support |
| Purity: | > 95% |
| Purification: | affinity purification |
| Format: | Lyophilized |
| Conjugate: | C-Mouse Fc tag |
| Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| Usage: | Research use only |
| Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
| Reconstitution: | Reconstitute with deionized water |
| Sequence: | Mouse BTLA（Glu30-Pro176) +mFc tag |
| Gene ID: | 208154 |
| Uniprot: | Q7TSA3 |
| Molecular Weight: | 55-70 kDa |
