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APC Anti-Mouse CD11a Antibody [FD441.8] (AGEL0832)

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SKU AGEL0832
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone FD441.8
Conjugation APC
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Description

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APC Anti-Mouse CD11a Antibody [FD441.8]

The Mouse CD11a Monoclonal Antibody (FD441.8) is a powerful tool for researchers studying immune cell adhesion and migration. This antibody, conjugated with APC, specifically targets CD11a, a cell surface protein involved in the formation of cell-cell interactions within the immune system. With its high specificity and affinity for mouse CD11a, this monoclonal antibody is ideal for flow cytometry and immunofluorescence applications.CD11a is a key integrin subunit that plays a crucial role in mediating leukocyte adhesion and transendothelial migration, processes essential for immune cell trafficking and immune responses. By targeting CD11a, researchers can investigate the mechanisms underlying immune cell adhesion and migration in various experimental settings.

This antibody's APC conjugation allows for easy and efficient detection of CD11a-positive cells, facilitating detailed analysis of immune cell behavior in vitro and in vivo.Through precise targeting of CD11a, researchers can gain insights into immune cell function in health and disease, paving the way for advancements in immunology, inflammation research, and autoimmune disease studies. The Mouse CD11a Monoclonal Antibody (FD441.8) is a valuable tool for unlocking the mysteries of immune cell interactions and holds great potential for enhancing our understanding of immune system dynamics.

Product Title:APC Anti-Mouse CD11a Antibody [FD441.8]
SKU:AGEL0832
Size:25µg, 100µg
Clone No:FD441.8
Synonyms:Integrin alpha-L;Itgal;CD11 antigen-like family member A;LFA-1A;Lymphocyte antigen 15;Ly-15;CD11a;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:APC Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P24063
Gene ID:16408
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11a is a 180 kD glycoprotein, also known as αL integrin, LFA-1 α, Ly-15, or Ly-21. It is a member of the integrin family, primarily expressed on lymphocytes, monocytes/macrophages, and granulocytes. In association with CD18, the CD11a/CD18 complex forms LFA-1. CD11a plays an important role in intercellular adhesion and costimulation by binding its ligands, ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).

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