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Purified Anti-Mouse CD11a Antibody [FD441.8] (AGEL0152)

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SKU AGEL0152
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Mouse
Host Species Rat
Isotype IgG2b
Clone FD441.8
Conjugation Unconjugated
Applications FC
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Description

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Purified Anti-Mouse CD11a Antibody [FD441.8]

The Mouse CD11a Monoclonal Antibody (FD441.8) (AGEL0152) offered by Assay Genie is a specialized reagent designed for research applications involving CD11a, a key integrin molecule essential for leukocyte adhesion and migration. This monoclonal antibody, generated from mouse hosts, exhibits high specificity and sensitivity in detecting CD11a in mouse samples, suitable for a range of experimental techniques.CD11a, also known as integrin alpha L, is a crucial cell surface receptor involved in mediating interactions between immune cells and endothelial cells during inflammatory responses. Its role in facilitating immune cell trafficking and activation underscores its importance in various physiological and pathological processes.

The Mouse CD11a Monoclonal Antibody enables precise identification and characterization of CD11a expression patterns, offering valuable insights into immune cell behavior in different biological contexts.This antibody's utility extends to investigations in immunology, inflammation, and infectious diseases, providing researchers with a reliable tool to study the functions of CD11a in diverse experimental settings. By elucidating the mechanisms governed by CD11a, scientists can deepen their understanding of immune cell dynamics and potentially uncover novel therapeutic targets for conditions influenced by immune cell behavior.

Product Title:Purified Anti-Mouse CD11a Antibody [FD441.8]
SKU:AGEL0152
Size:25µg, 100µg
Clone No:FD441.8
Synonyms:Integrin alpha-L;Itgal;CD11 antigen-like family member A;LFA-1A;Lymphocyte antigen 15;Ly-15;CD11a;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Purified Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Unconjugated
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P24063
Gene ID:16408
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11a is a 180 kD glycoprotein, also known as αL integrin, LFA-1 α, Ly-15, or Ly-21. It is a member of the integrin family, primarily expressed on lymphocytes, monocytes/macrophages, and granulocytes. In association with CD18, the CD11a/CD18 complex forms LFA-1. CD11a plays an important role in intercellular adhesion and costimulation by binding its ligands, ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).

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