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FITC Anti-Mouse CD11c Antibody [N418] (AGEL0513)

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SKU AGEL0513
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Armenian Hamster
Isotype IgG2a,k
Clone N418
Conjugation FITC
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Description

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FITC Anti-Mouse CD11c Antibody [N418]

The Mouse CD11c Monoclonal Antibody (FITC Conjugated) N418 (AGEL0513) is a specialized antibody designed for research applications involving the CD11c protein, a key marker for dendritic cells. This monoclonal antibody, labeled with FITC for fluorescence-based detection, offers high specificity and sensitivity for identifying CD11c in various mouse cell samples.CD11c is a well-established cell surface receptor predominantly expressed on dendritic cells, playing a crucial role in antigen presentation and immune responses. By targeting CD11c, researchers can efficiently study dendritic cell populations and their functions in immunity, inflammation, and autoimmune diseases.

The FITC conjugation of this antibody allows for easy visualization and quantification of CD11c-positive cells in flow cytometry, immunofluorescence, and other experimental techniques.By utilizing the Mouse CD11c Monoclonal Antibody (FITC Conjugated) N418 (AGEL0513), researchers can gain valuable insights into dendritic cell biology, immune system dynamics, and disease mechanisms. This antibody is a valuable tool for studies focusing on immunology, vaccine development, infectious diseases, and immunotherapy research.

Product Title:FITC Anti-Mouse CD11c Antibody [N418]
SKU:AGEL0513
Size:25µg, 100µg
Clone No:N418
Synonyms:Integrin alpha-X;Itgax;CD11 antigen-like family member C;Leukocyte adhesion receptor p150+95;CD11c;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:FITC Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q9QXH4
Gene ID:16411
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen and CD54.

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