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PE Anti-Mouse CD11c Antibody [N418] (AGEL0514)

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SKU AGEL0514
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Armenian Hamster
Isotype IgG2a,k
Clone N418
Conjugation PE
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Description

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PE Anti-Mouse CD11c Antibody [N418]

The Mouse CD11c Monoclonal Antibody (PE Conjugated, N418) is a valuable tool for researchers studying immune responses in mice. This antibody, generated against the CD11c protein, is conjugated to phycoerythrin (PE) for easy detection and analysis in flow cytometry experiments. CD11c is a marker commonly used to identify dendritic cells, a key immune cell population involved in antigen presentation and immune regulation.With its high specificity and sensitivity, the Mouse CD11c Monoclonal Antibody (PE Conjugated, N418) is suitable for a wide range of applications in immunology research.

It allows for precise detection and quantification of CD11c-expressing cells in various tissues and experimental models, aiding in the characterization of dendritic cell populations and their role in immune responses.This antibody is an essential tool for investigating immune cell dynamics, inflammatory processes, and immune cell subsets in mouse models. Its reliability and performance ensure accurate and reproducible results, making it an indispensable reagent for studies focusing on dendritic cell biology, immune responses, and vaccine development in preclinical research settings.

Product Title:PE Anti-Mouse CD11c Antibody [N418]
SKU:AGEL0514
Size:25µg, 100µg
Clone No:N418
Synonyms:Integrin alpha-X;Itgax;CD11 antigen-like family member C;Leukocyte adhesion receptor p150+95;CD11c;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:PE Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q9QXH4
Gene ID:16411
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen and CD54.

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