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Purified Anti-Mouse CD120b Antibody [TR75-54.7] (AGEL0161)

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SKU AGEL0161
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Mouse
Host Species Hamster
Isotype IgG
Clone TR75-54.7
Conjugation Unconjugated
Applications FC
Applications WB
Applications Block
Applications IP
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Description

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Purified Anti-Mouse CD120b Antibody [TR75-54.7]

The Mouse CD120b Monoclonal Antibody (TR75-54-7) is a specialized research tool offered by Assay Genie for scientists studying the CD120b protein in mouse samples. This monoclonal antibody, known as AGEL0161, is produced using hybridoma technology and is ideal for various applications, including immunohistochemistry, flow cytometry, and ELISA.The CD120b protein, also referred to as Tumor Necrosis Factor Receptor 2 (TNFR2), is a crucial component of the TNF signaling pathway, known for its role in inflammation, cell proliferation, and apoptosis. This antibody specifically targets CD120b, facilitating the detection and analysis of this protein in various cellular contexts.

Its high specificity and sensitivity make it a valuable tool for understanding the function of CD120b in immune responses and inflammatory conditions, providing insights for research in immunology, oncology, and autoimmune diseases.By utilizing the Mouse CD120b Monoclonal Antibody (TR75-54-7), researchers can delve deeper into the intricate mechanisms of TNF signaling and its implications in disease pathogenesis. With its reliability and specificity, this antibody empowers scientists to unravel the complexities of CD120b biology, paving the way for innovative therapeutic interventions and targeted treatments in the realm of immune-related disorders.

Product Title:Purified Anti-Mouse CD120b Antibody [TR75-54.7]
SKU:AGEL0161
Size:25µg, 100µg
Clone No:TR75-54.7
Synonyms:Tumor necrosis factor receptor superfamily member 1B;Tnfrsf1b;Tumor necrosis factor receptor 2;TNF-R2;TNF-RII;TNFR-II;p75;p80 TNF-alpha receptor;CD120b;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:Purified Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:Unconjugated
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P25119
Gene ID:21938
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD120b is a 75 kD type I transmembrane protein, also known as Tumor Necrosis Factor Receptor Type II (TNFRII) or p75. It is expressed on a variety of cells at low levels; the expression is upregulated upon activation. This receptor binds both TNF-α and LT-α (also known as TNF-β). In association with TRAF1 and TRAF2, the receptor crosslinking induced by TNF-α or LT-α trimers is critical for signal transduction, leading to apoptosis, NF-kB activation, increased expression of proinflammatory genes, tumor necrosis, and cell differentiation depending on cell type and differentiation state.

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