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PE/Cyanine5 Anti-Mouse CD122 Antibody [5H4] (AGEL0802)

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SKU AGEL0802
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone 5H4
Conjugation PE/Cy5
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Description

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PE/Cyanine5 Anti-Mouse CD122 Antibody [5H4]

The Mouse CD122 Monoclonal Antibody (PE/Cyanine5 Conjugated, 5H4) is a cutting-edge tool designed for researchers studying immune responses and cell signaling pathways. This antibody, provided by Assay Genie, is specifically engineered to target CD122, a key protein involved in the regulation of immune system function.CD122, also known as the Interleukin-2 receptor beta chain, plays a crucial role in the activation and proliferation of immune cells. By binding to CD122 with high specificity, the 5H4 antibody enables precise detection and analysis of this protein in various mouse cell types.

This makes it an invaluable resource for investigations spanning immunology, infectious diseases, and autoimmune disorders.By utilizing the Mouse CD122 Monoclonal Antibody (PE/Cyanine5 Conjugated, 5H4) in your research, you can gain deeper insights into the mechanisms underlying immune responses, paving the way for innovative therapies and interventions in fields such as cancer immunotherapy and autoimmune disease treatment. Trust in the quality and reliability of this antibody to advance your scientific endeavors and push the boundaries of knowledge in the realm of immunology.

Product Title:PE/Cyanine5 Anti-Mouse CD122 Antibody [5H4]
SKU:AGEL0802
Size:25µg, 100µg
Clone No:5H4
Synonyms:Interleukin-2 receptor subunit beta;Il2rb;IL-2 receptor subunit beta; IL-2R subunit beta;IL-2RB;High affinity IL-2 receptor subunit beta;p70-75;CD122;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine5 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P16297
Gene ID:16185
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.

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