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GenieFluor 488 Anti-Mouse CD127/IL-7RA Antibody [A7R34] (AGEL0753)

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SKU AGEL0753
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone A7R34
Conjugation AF 488
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Description

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GenieFluor 488 Anti-Mouse CD127/IL-7RA Antibody [A7R34]

The Mouse CD127 (IL-7Ra) Monoclonal Antibody (AF488 Conjugated, A7R34) is a cutting-edge tool for researchers studying immune system components in murine models. This antibody specifically targets CD127, also known as IL-7 receptor alpha, a crucial protein involved in T cell development and homeostasis.Developed for precise detection and analysis, the A7R34 antibody is conjugated with AF488 for enhanced visibility and sensitivity in fluorescence-based experiments. Its monoclonal nature ensures consistent performance and reliable results, making it a valuable asset in immunology research.CD127's role in T cell biology, particularly in promoting survival and function, makes it a key player in immune responses and autoimmune diseases.

By utilizing the A7R34 antibody, researchers can gain insights into the mechanisms underlying T cell regulation and explore potential therapeutic strategies targeting the IL-7 receptor pathway.Whether investigating T cell dynamics, analyzing lymphocyte populations, or studying autoimmune conditions, the Mouse CD127 (IL-7Ra) Monoclonal Antibody (AF488 Conjugated, A7R34) from AssayGenie provides a powerful tool for advancing scientific understanding in immunology and related fields.

Product Title:GenieFluor 488 Anti-Mouse CD127/IL-7RA Antibody [A7R34]
SKU:AGEL0753
Size:25µg, 100µg
Clone No:A7R34
Synonyms:Interleukin-7 receptor subunit alpha;Il7r;IL-7 receptor subunit alpha;IL-7R subunit alpha;IL-7R-alpha;IL-7RA;CD127;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Genie Fluor 488 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P16872
Gene ID:16197
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be an useful marker for identifying memory and effector T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cells proliferation and development.

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