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GenieFluor 647 Anti-Mouse CD127/IL-7RA Antibody [A7R34] (AGEL0754)

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SKU AGEL0754
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone A7R34
Conjugation AF 647
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Description

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GenieFluor 647 Anti-Mouse CD127/IL-7RA Antibody [A7R34]

The Mouse CD127 (IL-7RA) Monoclonal Antibody (AF647 Conjugated, A7R34, AGEL0754) offered by AssayGenie is a cutting-edge tool for immunological research. This antibody specifically targets the CD127 (IL-7RA) protein, a critical receptor involved in immune system function. By conjugating AF647 to the antibody, it enables precise visualization and detection of CD127 in samples, enhancing research capabilities.CD127, also known as the interleukin-7 receptor alpha chain, plays a key role in T cell development, survival, and homeostasis. The AF647 conjugated monoclonal antibody allows for the accurate identification and analysis of CD127 expression in various cell types and tissues, providing valuable insights into immune system regulation and function.

With its high specificity and sensitivity, this antibody is essential for studies related to immune responses, lymphocyte biology, and autoimmune diseases. Researchers in fields like immunology, oncology, and infectious diseases can utilize this tool to deepen their understanding of immune mechanisms and potentially uncover new therapeutic targets.Enhance your research capabilities with the Mouse CD127 (IL-7RA) Monoclonal Antibody AF647 Conjugated (A7R34, AGEL0754) from AssayGenie and unlock the potential for groundbreaking discoveries in the field of immunology.

Product Title:GenieFluor 647 Anti-Mouse CD127/IL-7RA Antibody [A7R34]
SKU:AGEL0754
Size:25µg, 100µg
Clone No:A7R34
Synonyms:Interleukin-7 receptor subunit alpha;Il7r;IL-7 receptor subunit alpha;IL-7R subunit alpha;IL-7R-alpha;IL-7RA;CD127;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Genie Fluor 647 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P16872
Gene ID:16197
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be an useful marker for identifying memory and effector T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cells proliferation and development.

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