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PE/Cyanine7 Anti-Mouse CD14 Antibody [Sa14-2] (AGEL1867)

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SKU AGEL1867
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone Sa14-2
Conjugation PE/Cy7
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Description

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PE/Cyanine7 Anti-Mouse CD14 Antibody [Sa14-2]

The Mouse CD14 Monoclonal Antibody (PE-Cyanine7 Conjugated) SA1-2 (AGEL1867) is a highly specialized tool for researchers studying CD14, a marker of monocyte and macrophage differentiation and activation in the immune system. This monoclonal antibody, conjugated to PE-Cyanine7 for enhanced detection, is specifically designed for flow cytometry applications in mouse samples.CD14 is a key component of the innate immune system, serving as a receptor for lipopolysaccharide (LPS) and other bacterial cell wall components. Its expression on monocytes and macrophages is crucial for the recognition and response to pathogens, triggering inflammatory signaling pathways.

With its precise targeting of CD14, this antibody allows for accurate identification and analysis of these specialized immune cells in experimental settings.Researchers in immunology, infection biology, and inflammation studies will find this antibody invaluable for investigating the role of CD14 in immune responses, infection control, and inflammatory diseases. By enabling the precise detection and characterization of CD14-expressing cells in mouse models, this monoclonal antibody contributes to the advancement of knowledge in immunological research and therapeutic development.

Product Title:PE/Cyanine7 Anti-Mouse CD14 Antibody [Sa14-2]
SKU:AGEL1867
Size:50 Tests, 100 Tests, 200 Tests
Clone No:Sa14-2
Synonyms:CD 14;Myeloid cell-specific leucine-rich glycoprotein;Monocyte differentiation antigen CD14;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine7 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P10810
Gene ID:12475
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed on macrophages, dendritic cells, Kupffer cells, hepatocytes, and granulocytes. As a high-affinity receptor for LPS-LBP (LPS-binding protein) complex, CD14, in association with Toll-like Receptor 4 (TLR4) or 2 (TLR2), is involved in the clearance of gram-negative pathogens.

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