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PE/Cyanine7 Anti-Mouse CD14 Antibody [Sa14-2] (AGEL1876)

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SKU AGEL1876
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone Sa14-2
Conjugation PE/Cy7
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Description

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PE/Cyanine7 Anti-Mouse CD14 Antibody [Sa14-2]

The Mouse CD14 Monoclonal Antibody (PE/Cyanine7 Conjugated) - SA14-2 (AGEL1876) is a powerful tool for researchers studying innate immune responses and macrophage biology. This antibody specifically targets the CD14 protein, a key component in the recognition of bacterial lipopolysaccharide (LPS) and the activation of innate immune responses.Derived from mouse cells, this monoclonal antibody is conjugated with PE/Cyanine7, allowing for easy detection and analysis by flow cytometry and fluorescence microscopy. Its high specificity and sensitivity make it an excellent choice for experiments requiring precise identification and quantification of CD14-expressing cells in various biological samples.

The CD14 protein is essential for the initiation of immune responses to bacterial infections and is also involved in inflammatory processes. By using this antibody, researchers can gain valuable insights into the role of CD14 in immune system signaling pathways, inflammation regulation, and disease development. This product is an invaluable asset for studies focusing on infectious diseases, immunology, and inflammation research.

Product Title:PE/Cyanine7 Anti-Mouse CD14 Antibody [Sa14-2]
SKU:AGEL1876
Size:25µg, 100µg
Clone No:Sa14-2
Synonyms:CD 14;Myeloid cell-specific leucine-rich glycoprotein;Monocyte differentiation antigen CD14;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine7 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P10810
Gene ID:12475
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed on macrophages, dendritic cells, Kupffer cells, hepatocytes, and granulocytes. As a high-affinity receptor for LPS-LBP (LPS-binding protein) complex, CD14, in association with Toll-like Receptor 4 (TLR4) or 2 (TLR2), is involved in the clearance of gram-negative pathogens.

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