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PE Anti-Mouse CD161/NK1.1 Antibody [PK136] (AGEL0485)

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SKU AGEL0485
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Mouse
Isotype IgG2a,k
Clone PK136
Conjugation PE
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Description

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PE Anti-Mouse CD161/NK1.1 Antibody [PK136]

The Mouse CD161/NK1.1 Monoclonal Antibody (PE Conjugated) is a cutting-edge tool designed for research applications involving the CD161/NK1.1 cell surface marker. This monoclonal antibody, designated as PK136-AGEL0485, is specifically tailored for use in flow cytometry, immunofluorescence, and cell sorting techniques. CD161, also known as NK1.1, is a marker commonly found on natural killer cells and subsets of T cells. It plays a pivotal role in immune surveillance and response against infections and tumors, making it a key molecule of interest in immunology research. The PE conjugation of this antibody allows for sensitive and specific detection of CD161/NK1.

1-expressing cells, enabling researchers to characterize and analyze immune cell populations with precision.With its high specificity and validated performance in various experimental assays, the Mouse CD161/NK1.1 Monoclonal Antibody (PE Conjugated) PK136-AGEL0485 is an invaluable tool for scientists studying immune cell biology, immunotherapy, and immune-related diseases. Its reliable performance and ability to target CD161/NK1.1 make it an essential reagent for advancing our understanding of immune responses and developing targeted approaches for immunomodulation and disease intervention.

Product Title:PE Anti-Mouse CD161/NK1.1 Antibody [PK136]
SKU:AGEL0485
Size:25µg, 100µg
Clone No:PK136
Synonyms:Killer cell lectin-like receptor subfamily B member 1C;Klrb1c;CD161 antigen-like family member C;Ly-55c;CD161/NK1.1;NKR-P1.9;NKR-P1C;NKR-P1 40;CD161c;
Host Species:Mouse
Reactivity:Mouse
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:PE Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P27814 P27812 Q99JB4
Gene ID:17059
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.

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