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APC Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173] (AGEL1430)

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SKU AGEL1430
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Armenian Hamster
Isotype IgG2a,k
Clone CXCR3-173
Conjugation APC
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Description

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APC Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]

The Mouse CD183 (CXCR3) Monoclonal Antibody (APC-conjugated) is a specialized tool for researchers studying the CXCR3 protein, an important chemokine receptor involved in immune responses and inflammation. This monoclonal antibody, known as CXCR3-173 (AGEL1430), is produced for use in flow cytometry applications and has been extensively validated for specificity and sensitivity in detecting CXCR3 in mouse samples.CXCR3 is a chemokine receptor that plays a critical role in recruiting immune cells to sites of inflammation and infection. By facilitating the migration and activation of T cells, CXCR3 contributes to the body's defense mechanisms against pathogens and tumor cells.

Research into CXCR3 function is vital for understanding immune responses in conditions such as autoimmune diseases, viral infections, and cancer.The APC-conjugated CXCR3-173 antibody offers a reliable method for identifying and analyzing CXCR3 expression on various cell types in mouse models. Its high specificity and fluorescence properties make it an excellent choice for flow cytometry experiments aimed at deciphering the role of CXCR3 in immune regulation and disease pathogenesis. Researchers can trust this monoclonal antibody to deliver accurate and reproducible results in their studies of CXCR3 biology.

Product Title:APC Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]
SKU:AGEL1430
Size:25µg, 100µg
Clone No:CXCR3-173
Synonyms:C-X-C chemokine receptor type 3;Cxcr3;CXC-R3;CXCR-3;Interferon-inducible protein 10 receptor;IP-10 receptor;CD183/CXCR3;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:APC Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:O88410
Gene ID:12766
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.

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