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PE Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173] (AGEL1429)

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SKU AGEL1429
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Armenian Hamster
Isotype IgG2a,k
Clone CXCR3-173
Conjugation PE
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Description

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PE Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]

The Mouse CD183 (CXCR3) Monoclonal Antibody (PE Conjugated), also known as CXCR3-173 (AGEL1429), is a specialized tool for research involving the mouse CXCR3 protein. CXCR3 is a chemokine receptor that plays a crucial role in immune responses, particularly in the context of inflammation and immune cell trafficking. This monoclonal antibody, conjugated with PE for fluorescent detection, is optimized for flow cytometry applications, allowing for precise and sensitive detection of CXCR3 expression in mouse cells.The unique specificity and high affinity of CXCR3-173 (AGEL1429) make it an ideal choice for investigating the role of CXCR3 in various immune-related studies, including inflammation, infectious diseases, and autoimmune disorders.

By targeting CXCR3, researchers can gain valuable insights into the underlying mechanisms of immune cell recruitment and activation, paving the way for the development of novel therapeutic strategies targeting CXCR3 signaling pathways. With its proven reliability and performance in flow cytometry assays, the Mouse CD183 (CXCR3) Monoclonal Antibody (PE Conjugated) is a valuable tool for scientists seeking to advance their understanding of immune responses and inflammatory processes in mouse models.

Product Title:PE Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]
SKU:AGEL1429
Size:25µg, 100µg
Clone No:CXCR3-173
Synonyms:C-X-C chemokine receptor type 3;Cxcr3;CXC-R3;CXCR-3;Interferon-inducible protein 10 receptor;IP-10 receptor;CD183/CXCR3;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:PE Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:O88410
Gene ID:12766
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.

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