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PE/Cyanine5 Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173] (AGEL1431)

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SKU AGEL1431
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Armenian Hamster
Isotype IgG2a,k
Clone CXCR3-173
Conjugation PE/Cy5
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Description

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PE/Cyanine5 Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]

The Mouse CD183 (CXCR3) Monoclonal Antibody PE-Cyanine5 Conjugated (CXCR3-173) is a cutting-edge tool for researchers working with CXCR3, a chemokine receptor that plays a crucial role in immune responses and inflammation. This monoclonal antibody, derived from mouse sources, is highly specific and reactive with mouse samples, making it ideal for flow cytometry and immunofluorescence applications. By binding to CXCR3, this antibody enables precise detection and analysis of this key receptor in various cell types, enabling detailed studies in immunology and inflammatory diseases.

CXCR3 is known for its involvement in directing immune cell migration and activation in response to inflammatory signals. Research on CXCR3 is essential for understanding the mechanisms of immune cell recruitment and activation in conditions such as autoimmune diseases, chronic inflammatory disorders, and certain types of cancer. By elucidating the functions of CXCR3, researchers can uncover potential therapeutic targets for modulating immune responses and inflammation in various disease contexts, ultimately paving the way for the development of novel treatment approaches.

Product Title:PE/Cyanine5 Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]
SKU:AGEL1431
Size:25µg, 100µg
Clone No:CXCR3-173
Synonyms:C-X-C chemokine receptor type 3;Cxcr3;CXC-R3;CXCR-3;Interferon-inducible protein 10 receptor;IP-10 receptor;CD183/CXCR3;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:O88410
Gene ID:12766
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.

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