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APC Anti-Mouse CD3ε Antibody [145-2C11] (AGEL1324)

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SKU AGEL1324
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Armenian Hamster
Isotype IgG2a,k
Clone 145-2C11
Conjugation APC
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Description

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APC Anti-Mouse CD3ε Antibody [145-2C11]

The Mouse CD3-Epsilon Monoclonal Antibody (APC Conjugated) is a powerful tool for researchers studying T-cell biology and immunology. This antibody, clone 145-2C11, is specifically designed to detect the CD3-epsilon antigen, a key component of the T-cell receptor complex.Ideal for flow cytometry applications, the Mouse CD3-Epsilon Monoclonal Antibody (APC Conjugated) offers high sensitivity and specificity in identifying and analyzing T cells in various samples. Its conjugation with allophycocyanin (APC) allows for easy and efficient detection using fluorescent microscopy or flow cytometry techniques.

The CD3-epsilon antigen is vital for T-cell activation and function, making this antibody indispensable for investigating T-cell responses in immune system studies, infectious diseases, and cancer research. With its reliable performance and accurate detection capabilities, the Mouse CD3-Epsilon Monoclonal Antibody (APC Conjugated) is a valuable asset for scientists exploring the intricacies of T-cell biology and immune responses.

Product Title:APC Anti-Mouse CD3ε Antibody [145-2C11]
SKU:AGEL1324
Size:25µg, 100µg
Clone No:145-2C11
Synonyms:T-cell surface glycoprotein CD3 epsilon chain;CD3E;T-cell surface antigen T3/Leu-4 epsilon chain;CD3e;CD3E;T3E;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:APC Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P22646
Gene ID:12501
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

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