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GenieFluor 647 Anti-Mouse CD3 Antibody [17A2] (AGEL0664)

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SKU AGEL0664
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone 17A2
Conjugation AF 647
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Description

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GenieFluor 647 Anti-Mouse CD3 Antibody [17A2]

The Mouse CD3 Monoclonal Antibody (AF647 Conjugated, 17A2) is a cutting-edge tool designed for precise research applications in immunology. This antibody, derived from hybridoma cells, targets the CD3 protein found on the surface of T cells in mice. By specifically binding to CD3, this antibody allows for the visualization and analysis of T cell populations in various experimental settings.CD3 is an essential component of the T cell receptor complex and plays a crucial role in T cell activation and signaling. By targeting CD3, researchers can investigate T cell function, activation, and response in immune-related studies.

The conjugation of AF647 enhances the antibody's utility by enabling fluorescent detection methods such as flow cytometry, immunofluorescence, and microscopy.The Mouse CD3 Monoclonal Antibody (AF647 Conjugated, 17A2) is a valuable asset for studies focused on T cell biology, immune responses, autoimmune diseases, and infections in mouse models. Its high specificity and sensitivity make it an indispensable tool for researchers seeking to unravel the complexities of T cell-mediated immune responses. Elevate your research with this innovative antibody and unlock new insights into the intricate world of immunology.

Product Title:GenieFluor 647 Anti-Mouse CD3 Antibody [17A2]
SKU:AGEL0664
Size:25µg, 100µg
Clone No:17A2
Synonyms:T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain;CD3E/D/G/Z;CD3e/d/g/z;CD3E/D/G/Z;CD3;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor 647 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P04235 P11942 P22646 P24161
Gene ID:12502
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

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