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APC Anti-Mouse CD3 Antibody [17A2] (AGEL0657)

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SKU AGEL0657
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone 17A2
Conjugation APC
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Description

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APC Anti-Mouse CD3 Antibody [17A2]

The Mouse CD3 Monoclonal Antibody (APC Conjugated, 17A2) from AssayGenie, labeled as AGEL0657, is a valuable tool for researchers in the field of immunology. This antibody specifically targets the CD3 protein, a crucial component of the T-cell receptor complex essential for T-cell activation and function.With its APC conjugation, this antibody is optimized for flow cytometry applications, allowing for the precise identification and analysis of T-cell populations in various samples. The APC conjugation enhances the sensitivity and specificity of the detection, making it ideal for studies requiring high-resolution analysis of T-cell subsets.This monoclonal antibody, developed using cutting-edge technology, offers researchers a reliable reagent for investigating T-cell biology, immune responses, and diseases related to T-cell dysfunction.

Its high specificity and performance have been validated through rigorous testing, ensuring accurate and reproducible results in experimental settings.Researchers focusing on T-cell biology, immune responses, autoimmune diseases, and infectious diseases can benefit from the precise and reliable detection provided by the Mouse CD3 Monoclonal Antibody (APC Conjugated, 17A2) from AssayGenie. This antibody opens up new possibilities for understanding the role of T-cells in immunity and disease pathogenesis, facilitating advancements in immunotherapy and precision medicine.

Product Title:APC Anti-Mouse CD3 Antibody [17A2]
SKU:AGEL0657
Size:25µg, 100µg
Clone No:17A2
Synonyms:T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain;CD3E/D/G/Z;CD3e/d/g/z;CD3E/D/G/Z;CD3;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:APC Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P04235 P11942 P22646 P24161
Gene ID:12502
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

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