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APC Anti-Mouse CD31 Antibody [390] (AGEL1911)

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SKU AGEL1911
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone 390
Conjugation APC
€107 - €275
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Description

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APC Anti-Mouse CD31 Antibody [390]

The Mouse CD31 Monoclonal Antibody (APC-conjugated) is a cutting-edge tool designed for researchers studying CD31, a key cell surface marker involved in vascular integrity and endothelial cell function. This high-quality antibody, derived from mouse monoclonal sources, exhibits excellent reactivity with mouse samples and is optimized for flow cytometry applications.CD31, also known as Platelet Endothelial Cell Adhesion Molecule (PECAM-1), plays a crucial role in mediating endothelial cell adhesion and signaling, essential for processes such as angiogenesis, immune cell recruitment, and vascular permeability. Dysregulation of CD31 expression has been linked to various vascular disorders, inflammatory conditions, and tumor angiogenesis.

By targeting the CD31 protein, this antibody enables precise detection and analysis of CD31 expression in mouse tissue samples, making it an invaluable tool for researchers investigating vascular biology, inflammation, and tumor microenvironment. Its specificity and reliability make it an ideal choice for studies aiming to decipher the role of CD31 in physiological and pathological processes, paving the way for potential therapeutic interventions targeting vascular-related diseases.

Product Title:APC Anti-Mouse CD31 Antibody [390]
SKU:AGEL1911
Size:50 Tests, 100 Tests, 200 Tests
Clone No:390
Synonyms:Pecam; Pecam-1;PECAM-1;CD31;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:APC Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q08481
Gene ID:18613
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD31 is a 130-140 kD glycoprotein, also known as platelet endothelial cell adhesion molecule (PECAM-1) and EndoCAM. It is a member of the Ig superfamily, expressed on endothelial cells, platelets, granulocytes, monocytes/macrophages, dendritic cells, and T and B cell subsets, and is critical for cell-cell interactions. The primary ligands for CD31 have been reported to be CD38 and the vitronectin receptor (αv β3 integrin, CD51/CD61). Other reported functions of CD31 are neutrophil emigration to sites of inflammation and angiogenesis.

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