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PE Anti-Mouse CD31 Antibody [390] (AGEL1919)

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SKU AGEL1919
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone 390
Conjugation PE
€75 - €210
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Description

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PE Anti-Mouse CD31 Antibody [390]

The Mouse CD31 Monoclonal Antibody (PE Conjugated) is a specialized tool for researchers investigating CD31, a crucial cell surface marker involved in vascular biology and immune response regulation. This antibody, developed specifically for mouse samples, offers exceptional sensitivity and specificity in flow cytometry and immunofluorescence applications. By targeting the CD31 protein, it facilitates the identification and characterization of endothelial cells, leukocytes, and hematopoietic stem cells, making it indispensable for studies in angiogenesis, inflammation, and hematopoiesis.CD31, also known as platelet endothelial cell adhesion molecule-1 (PECAM-1), is key in mediating cell adhesion, migration, and signal transduction within the vascular system. Its diverse functions in maintaining vascular integrity, modulating immune responses, and regulating thrombosis highlight its importance in various physiological and pathological processes.

Research focused on CD31 provides insights into vascular diseases, inflammatory disorders, and immune-mediated conditions, guiding the development of targeted interventions and therapies.The Mouse CD31 Monoclonal Antibody (PE Conjugated) from Assay Genie offers researchers a reliable tool to explore the multifaceted roles of CD31 in health and disease, advancing our understanding of vascular biology and immunology. Trust this antibody for precise and reproducible results in your experiments, driving forward discoveries in cardiovascular health, immune modulation, and therapeutic strategies.

Product Title:PE Anti-Mouse CD31 Antibody [390]
SKU:AGEL1919
Size:25µg, 100µg
Clone No:390
Synonyms:Pecam; Pecam-1;PECAM-1;CD31;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q08481
Gene ID:18613
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD31 is a 130-140 kD glycoprotein, also known as platelet endothelial cell adhesion molecule (PECAM-1) and EndoCAM. It is a member of the Ig superfamily, expressed on endothelial cells, platelets, granulocytes, monocytes/macrophages, dendritic cells, and T and B cell subsets, and is critical for cell-cell interactions. The primary ligands for CD31 have been reported to be CD38 and the vitronectin receptor (αv β3 integrin, CD51/CD61). Other reported functions of CD31 are neutrophil emigration to sites of inflammation and angiogenesis.

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