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GenieFluor 647 Anti-Mouse CD4 Antibody [GK1.5] (AGEL1254)

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SKU AGEL1254
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone GK1.5
Conjugation AF 647
€100 - €238
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Description

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GenieFluor 647 Anti-Mouse CD4 Antibody [GK1.5]

The Mouse CD4 Monoclonal Antibody (AF647-conjugated GK1.5, AGEL1254) is a valuable tool for researchers studying immune responses and T cell biology. This antibody specifically targets the CD4 cell surface marker, a key protein involved in T cell activation and differentiation.Designed for use in flow cytometry and immunofluorescence applications, this monoclonal antibody provides high sensitivity and specificity in detecting CD4-expressing cells in both mouse tissue samples and cell cultures. The AF647 conjugation allows for efficient and reliable fluorescent labeling, making it ideal for multiplexing experiments and cellular imaging studies.

The CD4 protein is crucial for mediating interactions between T cells and antigen-presenting cells, playing a central role in the adaptive immune response. Understanding the expression and function of CD4 cells is essential for unraveling the complex mechanisms governing immune surveillance, tolerance, and autoimmune diseases.By using the Mouse CD4 Monoclonal Antibody (AF647-conjugated GK1.5, AGEL1254), researchers can explore the dynamic behavior of CD4-positive T cells in various experimental settings, advancing our knowledge of immune system regulation and the development of targeted therapies for immune-related disorders.

Product Title:GenieFluor 647 Anti-Mouse CD4 Antibody [GK1.5]
SKU:AGEL1254
Size:25µg, 100µg
Clone No:GK1.5
Synonyms:T-cell surface glycoprotein CD4;T-cell surface antigen T4/Leu-3;L3T4;T4;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor 647 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P06332
Gene ID:12504
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD4 is a 55 kD protein also known as L3T4 or T4. It is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosin kinase, lck.

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