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GenieFluor 488 Anti-Mouse CD45 Antibody [30-F11] (AGEL1665)

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SKU AGEL1665
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone 30-F11
Conjugation AF 488
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Description

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GenieFluor 488 Anti-Mouse CD45 Antibody [30-F11]

The Mouse CD45 Monoclonal Antibody (AF488 Conjugated) 30-F11 (AGEL1665) is a cutting-edge tool designed for researchers investigating the CD45 protein in mouse samples. CD45, also known as leukocyte common antigen, is a crucial cell surface marker found on all white blood cells. This monoclonal antibody, conjugated with AF488 for fluorescence detection, specifically targets CD45 in mouse tissues or cell cultures.With its high specificity and sensitivity, this antibody is ideal for various applications such as flow cytometry, immunofluorescence, and immunohistochemistry. By binding to the CD45 antigen, researchers can accurately quantify and analyze white blood cells, characterize immune cell populations, and track cell surface marker expression in mouse models.

This antibody is a valuable asset for studies in immunology, cancer research, and immune cell characterization.Understanding the role of CD45 in immune cell function is essential for unraveling the complexities of immune responses, inflammation, and disease pathology. By utilizing the Mouse CD45 Monoclonal Antibody (AF488 Conjugated) 30-F11 (AGEL1665), researchers can delve deeper into the mechanisms underlying immune system regulation, paving the way for innovative discoveries and potential therapeutic interventions in various disease settings.

Product Title:GenieFluor 488 Anti-Mouse CD45 Antibody [30-F11]
SKU:AGEL1665
Size:50 Tests, 100 Tests, 200 Tests
Clone No:30-F11
Synonyms:Receptor-type tyrosine-protein phosphatase C;Ptprc;L-CA;Ly-5;T200;CD45;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor 488 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P06800
Gene ID:19264
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from alternative splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

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