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APC Anti-Mouse CD45 Antibody [30-F11] (AGEL1659)

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SKU AGEL1659
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone 30-F11
Conjugation APC
€50 - €157
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Description

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APC Anti-Mouse CD45 Antibody [30-F11]

The Mouse CD45 Monoclonal Antibody (APC Conjugated, 30-F11) is a powerful tool for researchers studying immune cells in mice. This antibody, designated AGEL1659, specifically targets the CD45 protein, a key marker for identifying leukocytes in flow cytometry and immunofluorescence applications. By conjugating the antibody to allophycocyanin (APC), it enables sensitive and precise detection of CD45 on cell surfaces, aiding in the characterization and analysis of immune cell populations.CD45, also known as leukocyte common antigen, is a crucial component for immune cell function and activation.

Its expression pattern and isoform diversity make it a versatile tool for delineating immune cell subsets and understanding their role in various physiological and pathological conditions. The Mouse CD45 Monoclonal Antibody (APC Conjugated, 30-F11) offers researchers a reliable method to study immune responses, inflammation, and hematopoiesis in mouse models, contributing to advancements in immunology, infectious diseases, and cancer research.

Product Title:APC Anti-Mouse CD45 Antibody [30-F11]
SKU:AGEL1659
Size:50 Tests, 100 Tests, 200 Tests
Clone No:30-F11
Synonyms:Receptor-type tyrosine-protein phosphatase C;Ptprc;L-CA;Ly-5;T200;CD45;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:APC Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P06800
Gene ID:19264
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from alternative splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

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