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FITC Anti-Mouse CD45 Antibody [30-F11] (AGEL1657)

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SKU AGEL1657
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone 30-F11
Conjugation FITC
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Description

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FITC Anti-Mouse CD45 Antibody [30-F11]

The Mouse CD45 Monoclonal Antibody FITC Conjugated (30-F11, AGEL1657) is a powerful tool designed for researchers studying CD45, a key protein involved in immune cell function. This monoclonal antibody, derived from mouse hybridoma cells, is conjugated with FITC for fluorescence detection, allowing for precise visualization and analysis of CD45 expression in various experimental settings.CD45, also known as leukocyte common antigen, is a critical marker for identifying and characterizing different immune cell populations. Its expression levels can provide valuable insights into immune cell activation, differentiation, and signaling pathways. The Mouse CD45 Monoclonal Antibody FITC Conjugated (30-F11, AGEL1657) specifically targets CD45, enabling researchers to accurately detect and quantify this important marker in samples from mouse tissues or cell cultures.

This antibody is well-suited for a range of applications, including flow cytometry, immunofluorescence microscopy, and immunoblotting. Its high specificity and sensitivity make it an ideal choice for studies focused on immunology, inflammation, hematopoiesis, and related fields. By utilizing this monoclonal antibody, researchers can gain deeper insights into the role of CD45 in immune responses, disease pathogenesis, and potential therapeutic interventions.

Product Title:FITC Anti-Mouse CD45 Antibody [30-F11]
SKU:AGEL1657
Size:50 Tests, 100 Tests, 200 Tests
Clone No:30-F11
Synonyms:Receptor-type tyrosine-protein phosphatase C;Ptprc;L-CA;Ly-5;T200;CD45;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:FITC Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P06800
Gene ID:19264
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from alternative splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

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