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PE/Cyanine5.5 Anti-Mouse CD45 Antibody [30-F11] (AGEL1673)

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SKU AGEL1673
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone 30-F11
Conjugation PE/Cy5.5
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Description

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PE/Cyanine5.5 Anti-Mouse CD45 Antibody [30-F11]

The Mouse CD45 Monoclonal Antibody PE-Cyanine5.5 Conjugated (30-F11) is a vital tool for researchers studying immune cells in mice. This antibody, conjugated to PE-Cyanine5.5, specifically targets the CD45 protein expressed on the surface of leukocytes, making it an ideal choice for flow cytometry and immunofluorescence applications.CD45, also known as the leukocyte common antigen, is a marker for immune cell lineage and activation status. The 30-F11 antibody is highly reactive and specific to CD45 in mouse samples, allowing for accurate detection and analysis of immune cell populations in various tissues and experimental conditions.

By using the Mouse CD45 Monoclonal Antibody PE-Cyanine5.5 Conjugated (30-F11), researchers can confidently study immune cell subpopulations, investigate immune responses, and monitor immune cell activation in mouse models of disease. This antibody is a valuable tool for immunologists, oncologists, and researchers studying autoimmune disorders, infectious diseases, and inflammatory conditions in preclinical research settings.

Product Title:PE/Cyanine5.5 Anti-Mouse CD45 Antibody [30-F11]
SKU:AGEL1673
Size:25µg, 100µg
Clone No:30-F11
Synonyms:Receptor-type tyrosine-protein phosphatase C;Ptprc;L-CA;Ly-5;T200;CD45;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE/Cyanine5.5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P06800
Gene ID:19264
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from alternative splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

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