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GenieFluor 488 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1] (AGEL1416)

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SKU AGEL1416
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone RA3.3A 1/6.1
Conjugation AF 488
€105 - €238
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Description

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GenieFluor 488 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]

The Mouse CD45R/B220 Monoclonal Antibody (AF488 Conjugated) RA3-3A1 (6.1) (AGEL1416) is a highly specific antibody designed for research in immunology. This monoclonal antibody, conjugated with AF488 for fluorescent detection, targets the CD45R/B220 protein, which is a marker for B cells in mice. CD45R/B220 is a surface protein found on B lymphocytes and is involved in B cell development, activation, and differentiation. By binding specifically to CD45R/B220, this antibody enables precise detection and analysis of B cells in various cell types and tissues, making it an invaluable tool for studies related to B cell biology, immunology, and autoimmune diseases.

With its high specificity and reliable performance, the Mouse CD45R/B220 Monoclonal Antibody (AF488 Conjugated) RA3-3A1 (6.1) (AGEL1416) is ideal for flow cytometry, immunofluorescence, and other applications where accurate identification and characterization of B cells are essential. Researchers interested in investigating B cell function, development, and diseases will find this antibody to be a valuable asset in their experimental work.

Product Title:GenieFluor 488 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]
SKU:AGEL1416
Size:25µg, 100µg
Clone No:RA3.3A 1/6.1
Synonyms:B220;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgM, κ
Isotype Control:Genie Fluor 488 Rat IgM, κ Isotype Control[RTK2118]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Gene ID:19264,5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.

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