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GenieFluor 647 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1] (AGEL1417)

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SKU AGEL1417
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone RA3.3A 1/6.1
Conjugation AF 647
€105 - €238
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Description

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GenieFluor 647 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]

The Mouse CD45R (B220) Monoclonal Antibody (AF647 Conjugated) is a valuable tool for researchers investigating immune cell markers and populations. This antibody, clone RA3-6B2, specifically targets CD45R (also known as B220), a protein found predominantly on B cells and a subset of T cells in mice.CD45R (B220) is a commonly used marker for identifying B cells in flow cytometry and immunohistochemistry studies. Its expression pattern can provide insights into B cell development, activation, and function within the immune system.

The AF647 conjugate of this monoclonal antibody allows for highly sensitive and specific detection of CD45R (B220) in experimental samples.By using the Mouse CD45R (B220) Monoclonal Antibody (AF647 Conjugated), researchers can enhance their understanding of B cell biology, immune responses, and disease mechanisms in mouse models. This antibody is a reliable reagent for studies in immunology, cancer research, and other fields where the characterization of B cell populations is essential for scientific progress.

Product Title:GenieFluor 647 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]
SKU:AGEL1417
Size:25µg, 100µg
Clone No:RA3.3A 1/6.1
Synonyms:B220;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgM, κ
Isotype Control:Genie Fluor 647 Rat IgM, κ Isotype Control[RTK2118]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Gene ID:19264,5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.

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