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FITC Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1] (AGEL1401)

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SKU AGEL1401
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone RA3.3A 1/6.1
Conjugation FITC
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Description

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FITC Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]

The Mouse CD45R/B220 Monoclonal Antibody FITC Conjugated (RA3-6B2) is an essential tool for immunological research, specifically targeting the CD45R/B220 protein found on lymphocytes and B cells. This FITC-conjugated antibody, recognized by the RA3-6B2 clone, offers high specificity and sensitivity in detecting and analyzing CD45R/B220 expression in various mouse cell types.CD45R/B220 is a well-known marker for B cell subsets and plays a crucial role in B cell development, activation, and differentiation. By utilizing this monoclonal antibody, researchers can precisely identify and characterize B cell populations in immunological studies, aiding in the understanding of immune responses, autoimmunity, and lymphoproliferative disorders.

The RA3-6B2 Monoclonal Antibody FITC Conjugated is a reliable tool for flow cytometry and immunofluorescence applications, providing valuable insights into the functional and phenotypic characteristics of B cells in mouse models. With its exceptional performance and versatility, this antibody is a valuable asset for researchers investigating B cell biology, immunology, and related fields.

Product Title:FITC Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]
SKU:AGEL1401
Size:50 Tests, 100 Tests, 200 Tests
Clone No:RA3.3A 1/6.1
Synonyms:B220;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgM, κ
Isotype Control:FITC Rat IgM, κ Isotype Control[RTK2118]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Gene ID:19264,5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.

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