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PE/Cyanine5 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1] (AGEL1412)

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SKU AGEL1412
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone RA3.3A 1/6.1
Conjugation PE/Cy5
€75 - €238
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Description

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PE/Cyanine5 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]

The Mouse CD45R/B220 Monoclonal Antibody (PE/Cyanine5 Conjugated) - RA3-3A1, 6.1 (AGEL1412) is a specialized antibody designed for research involving the CD45R/B220 molecule in mice. This monoclonal antibody has been conjugated with PE/Cyanine5, allowing for easy visualization and detection in flow cytometry and immunofluorescence applications. CD45R/B220 is a commonly used cell surface marker for identifying B cells in mice, playing a crucial role in the immune system. This highly specific antibody, clone RA3-3A1, 6.1, recognizes and binds to the CD45R/B220 protein, providing researchers with a valuable tool for studying B cell development, activation, and function in various experimental settings.

With its high sensitivity and specificity, the Mouse CD45R/B220 Monoclonal Antibody (PE/Cyanine5 Conjugated) - RA3-3A1, 6.1 (AGEL1412) is an essential reagent for immunologists, cell biologists, and researchers interested in investigating the role of B cells in immune responses, autoimmune diseases, and cancer. Its versatile applications make it a valuable asset in understanding the complexities of the immune system in mice, driving advancements in immunology and biomedical research.

Product Title:PE/Cyanine5 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]
SKU:AGEL1412
Size:25µg, 100µg
Clone No:RA3.3A 1/6.1
Synonyms:B220;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgM, κ
Isotype Control:PE/Cyanine5 Rat IgM, κ Isotype Control[RTK2118]
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Gene ID:19264,5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.

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