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FITC Anti-Mouse CD49b Antibody [DX5] (AGEL1445)

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SKU AGEL1445
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone DX5
Conjugation FITC
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Description

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FITC Anti-Mouse CD49b Antibody [DX5]

The Mouse CD49b Monoclonal Antibody (FITC Conjugated, DX5, AGEL1445) offered by AssayGenie is a valuable tool for researchers studying immune cells and their functions. This antibody specifically targets CD49b, also known as Integrin alpha-2, a cell surface protein involved in cell adhesion and migration.CD49b is a critical molecule in the immune system, playing a role in regulating the migration and activation of various immune cells. By utilizing this monoclonal antibody, researchers can specifically detect and analyze the presence of CD49b in their experimental samples.

The FITC conjugation allows for easy visualization and detection using fluorescence-based techniques.This antibody is ideal for flow cytometry and immunofluorescence applications, providing researchers with a reliable tool to study immune cell populations and their interactions. With its high specificity and sensitivity, the Mouse CD49b Monoclonal Antibody (FITC Conjugated, DX5, AGEL1445) from AssayGenie is a valuable resource for immunology research, drug development, and understanding the mechanisms underlying immune responses.

Product Title:FITC Anti-Mouse CD49b Antibody [DX5]
SKU:AGEL1445
Size:25µg, 100µg
Clone No:DX5
Synonyms:Integrin alpha-2;CD49 antigen-like family member B;Collagen receptor;Platelet membrane glycoprotein Ia;GPIa;VLA-2 subunit alpha;CD49b;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgM, κ
Isotype Control:FITC Rat IgM, κ Isotype Control[RTK2118]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q62469
Gene ID:16398
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.

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