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PE/Cyanine5.5 Anti-Mouse CD49b Antibody [DX5] (AGEL1451)

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SKU AGEL1451
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Mouse
Applications FC
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Description

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PE/Cyanine5.5 Anti-Mouse CD49b Antibody [DX5]

The Dx5-PE/Cyanine5.5 Conjugated Mouse CD49b Monoclonal Antibody (AGEL1451) from Assay Genie is a high-quality antibody designed for the detection of CD49b, a cell surface protein involved in cell adhesion and migration processes. This monoclonal antibody is conjugated with PE/Cyanine5.5, allowing for fluorescent visualization in flow cytometry applications. The antibody is specifically designed for use in mouse samples and has been rigorously validated for its specificity and sensitivity.CD49b, also known as integrin alpha-2, plays a crucial role in cell-cell and cell-matrix interactions, making it a key player in various biological processes such as wound healing, immune response, and tumor metastasis.

By targeting CD49b with this specialized monoclonal antibody, researchers can accurately identify and study this important protein in different biological contexts, including immunology, oncology, and developmental biology.With its high reactivity and specificity, the Dx5-PE/Cyanine5.5 Conjugated Mouse CD49b Monoclonal Antibody (AGEL1451) is an essential tool for scientists and researchers aiming to explore the functions and mechanisms of CD49b in a wide range of research applications. Enhance your experiments and advance your studies with this reliable and versatile antibody from Assay Genie.

Product Title:PE/Cyanine5.5 Anti-Mouse CD49b Antibody [DX5]
SKU:AGEL1451
Size:25µg, 100µg
Clone No:DX5
Synonyms:Integrin alpha-2;CD49 antigen-like family member B;Collagen receptor;Platelet membrane glycoprotein Ia;GPIa;VLA-2 subunit alpha;CD49b;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgM, κ
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q62469
Gene ID:16398
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.

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