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Key Features

PerCP/Cyanine5.5 Anti-Mouse CD49b Antibody [DX5] (AGEL1452)

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SKU AGEL1452
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone DX5
Conjugation PerCP/Cy5.5
€150 - €357
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Description

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PerCP/Cyanine5.5 Anti-Mouse CD49b Antibody [DX5]

The Mouse CD49b Monoclonal Antibody (PerCP-Cyanine5.5 Conjugated, DX5, AGEL1452) is a specialized research tool designed for the study of CD49b, a cell surface molecule known to be involved in immune responses and cell adhesion processes. This monoclonal antibody, formulated for use in flow cytometry applications, is produced using cutting-edge techniques to ensure high specificity and sensitivity in detecting CD49b in mouse samples.CD49b, also referred to as integrin alpha-2 or very late antigen-2 (VLA-2), is a key player in immune cell interactions and tissue homing processes. Its role in mediating adhesion and migration of immune cells makes it a crucial target for understanding immune-mediated diseases, such as inflammation, autoimmune disorders, and cancer metastasis.

By utilizing the Mouse CD49b Monoclonal Antibody, researchers can accurately identify and quantify CD49b expression in various cell populations, aiding in the investigation of immune responses and disease mechanisms.This antibody is an essential tool for immunologists, oncologists, and researchers studying cell adhesion and immune system regulation. With its high quality and specificity, the Mouse CD49b Monoclonal Antibody offers reliable results and valuable insights into the functions of CD49b in health and disease.

Product Title:PerCP/Cyanine5.5 Anti-Mouse CD49b Antibody [DX5]
SKU:AGEL1452
Size:25µg, 100µg
Clone No:DX5
Synonyms:Integrin alpha-2;CD49 antigen-like family member B;Collagen receptor;Platelet membrane glycoprotein Ia;GPIa;VLA-2 subunit alpha;CD49b;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgM, κ
Form:Liquid
Conjugation:PerCP/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q62469
Gene ID:16398
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.

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