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PE/Cyanine7 Anti-Mouse CD5 Antibody [53-7.3] (AGEL1955)

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SKU AGEL1955
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone 53-7.3
Conjugation PE/Cy7
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Description

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PE/Cyanine7 Anti-Mouse CD5 Antibody [53-7.3]

The Mouse CD5 Monoclonal Antibody PE-Cyanine7 Conjugated (53-7.3) is a valuable tool for research involving the CD5 molecule, a cell surface receptor primarily expressed on T cells and B-1a cells. This antibody, derived from mouse hybridoma cells, is conjugated with PE-Cyanine7 for fluorescent detection and flow cytometry applications, enabling precise analysis of CD5 expression in various immune cell populations.CD5, a transmembrane glycoprotein, is a key regulator of T and B cell activation and tolerance. Its involvement in modulating signal transduction pathways and immune responses makes it a crucial target for investigations in immunology, autoimmunity, and B cell malignancies.

By specifically binding to CD5, this antibody facilitates the identification and characterization of CD5-expressing cells, aiding in the study of immune cell development, activation, and dysregulation in disease states.Research utilizing the Mouse CD5 Monoclonal Antibody PE-Cyanine7 Conjugated (53-7.3) can provide insights into the roles of CD5 in immune system function and dysfunction, paving the way for the development of targeted therapies for immune-related disorders and cancer. Its high specificity and fluorescence properties make it a reliable reagent for immunophenotyping and investigating the complex interplay of immune cells in health and disease.

Product Title:PE/Cyanine7 Anti-Mouse CD5 Antibody [53-7.3]
SKU:AGEL1955
Size:50 Tests, 100 Tests, 200 Tests
Clone No:53-7.3
Synonyms:Ly-1;Lyt-1;Lymphocyte antigen 1;CD5;Cd5;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine7 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P13379
Gene ID:12507
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD5 is a 67 kD protein, also known as Lyt-1, Ly-1, T1, Tp67, or Ly-12. It is a member of the scavenger receptor cysteine-rich protein superfamily (SRCR) and primarily expressed on thymocytes, T cells, and B-1 cells. Although mature α/β T cells express high levels of CD5, very few γ/δ T cells express this antigen. The interaction of CD5 with CD72, gp35-37, TCR, or BCR is involved in T and B cell activation.

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