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GenieFluor 488 Anti-Mouse CD54 Antibody [YN1/1.7.4] (AGEL0718)

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SKU AGEL0718
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone YN1/1.7.4
Conjugation AF 488
€100 - €238
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Description

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GenieFluor 488 Anti-Mouse CD54 Antibody [YN1/1.7.4]

The Mouse CD54 Monoclonal Antibody (AF488 conjugated, YN1/1.7.4) from Assay Genie (AGEL0718) is an essential tool for researchers studying cell adhesion molecules and immune responses in mouse models.This monoclonal antibody specifically targets CD54, also known as intercellular adhesion molecule 1 (ICAM-1), a key protein involved in cell-cell interactions and immune cell recruitment. By conjugating it with AF488, a fluorescent dye, this antibody allows for visualization and tracking of CD54 expression in tissues and cells.CD54 plays a crucial role in inflammatory responses, immune cell trafficking, and the activation of immune cells.

By targeting CD54 with this monoclonal antibody, researchers can gain valuable insights into the mechanisms underlying immune-related processes and diseases. Whether studying inflammation, infection, or immunotherapy, the Mouse CD54 Monoclonal Antibody (AF488 conjugated, YN1/1.7.4) provides a reliable tool for accurate detection and analysis.Order your Mouse CD54 Monoclonal Antibody (AF488 conjugated, YN1/1.7.4) from Assay Genie today and accelerate your research in immunology, inflammation, and beyond.

Product Title:GenieFluor 488 Anti-Mouse CD54 Antibody [YN1/1.7.4]
SKU:AGEL0718
Size:25µg, 100µg
Clone No:YN1/1.7.4
Synonyms:Intercellular adhesion molecule 1;Icam1;MALA-2;MyD10;CD54;Icam-1;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor 488 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P13597
Gene ID:15894
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD54 is a 90 kD immunoglobulin superfamily member also known as ICAM-1 and Ly-47. It is expressed on activated endothelial cells, high endothelial venules (HEV), T and B cells, monocytes/ macrophages, granulocytes, and dendritic cells. CD54 is an important intracellular adhesion molecule that participates in T cell-T cell, T cell-B cell, and T cell-target cell interactions via binding of LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). CD54 has also been shown to be involved in lymphocyte trafficking, making it an important molecule in many immune reactions and inflammation. CD54 is also a receptor for rhinovirus. The YN1/1.7.4 antibody has been reported to block binding of mouse CD54 to LFA-1 and Mac-1, inhibit cell-cell adhesion, and function in antigen presentation to T cells and leukocyte migration to inflammatory tissues.

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