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GenieFluor 647 Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219] (AGEL1195)

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SKU AGEL1195
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone R17 217.1.3/TIB-219
Conjugation AF 647
€123 - €344
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Description

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GenieFluor 647 Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219]

The Mouse CD71 Monoclonal Antibody (AF647 Conjugated, R17-217.1-3, Tib-219) is a vital tool for researchers studying CD71, a cell surface protein involved in iron uptake and metabolism. This antibody, conjugated with Alexa Fluor 647, is ideal for flow cytometry and fluorescence microscopy applications. It specifically binds to the CD71 protein, allowing for precise detection and visualization in various mouse cell types.CD71, also known as transferrin receptor 1, plays a crucial role in regulating iron homeostasis and is essential for cell proliferation and growth.

Understanding the expression and function of CD71 is key in research areas such as cell biology, cancer biology, and iron metabolism disorders. This antibody provides researchers with a reliable tool to study the role of CD71 in physiological processes and disease mechanisms, contributing to advancements in biomedical research and potential therapeutic interventions.

Product Title:GenieFluor 647 Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219]
SKU:AGEL1195
Size:50 Tests, 100 Tests, 200 Tests
Clone No:R17 217.1.3/TIB-219
Synonyms:Transferrin receptor protein 1;Tfrc;TR;TfR;TfR1;Trfr;CD71;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Genie Fluor 647 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q62351
Gene ID:22042
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD71 is a 95 kD type II heterodimeric transmembrane glycoprotein that is also known as T9 and transferrin receptor. CD71 is expressed on proliferating cells, reticulocytes, and erythroid precursors. Its expression is very low on resting leukocytes. CD71 plays a role in the control of cellular proliferation by facilitating the uptake of iron via ferrotransferrin binding and the recycling of apotransferrin to the cell surface.

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