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PE Anti-Mouse CD90.2 Antibody [30H12] (AGEL1213)

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SKU AGEL1213
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone 30H12
Conjugation PE
€53 - €150
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Description

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PE Anti-Mouse CD90.2 Antibody [30H12]

The Mouse CD90.2 Monoclonal Antibody (PE Conjugated, 30-H12) is a valuable tool for researchers studying CD90.2, a cell surface marker commonly used to identify and isolate mouse T cells, stem cells, and other immune cell subsets. This monoclonal antibody, conjugated to Phycoerythrin (PE), offers high specificity and sensitivity in flow cytometry applications, allowing for precise labeling and analysis of CD90.2-expressing cells in various biological samples.CD90.2, also known as Thy-1.2 antigen, plays a crucial role in cell-cell interactions, cellular adhesion, and signal transduction processes within the immune system.

Its expression pattern and functional significance make it a key target for investigating immune responses, stem cell biology, and immunotherapy approaches in preclinical and translational research settings. By utilizing the Mouse CD90.2 Monoclonal Antibody, researchers can gain insights into the behavior and function of CD90.2-positive cells, advancing our understanding of immune regulation and therapeutic development mechanisms in health and disease contexts.

Product Title:PE Anti-Mouse CD90.2 Antibody [30H12]
SKU:AGEL1213
Size:25µg, 100µg
Clone No:30H12
Synonyms:Thy-1.2 membrane glycoprotein;Thy1.2;Thy-1.2 antigen;CD90.2;Thy-1.2;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Gene ID:21838
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD90.2 is a 25-35 kD immunoglobulin superfamily member also known as Thy1.2. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells in Thy1.2 bearing mouse strains (Balb/c, CBA/J, C3H/He, C57BL/-, DBA, NZB/-). CD90.2 is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein involved in signal transduction. CD90.2 is involved in costimulation of lymphocyte proliferation and induction of hematopoietic stem cells differentiation. CD90.2 has been shown to interact with CD45. The 30H12 antibody has been reported to induce Ca2+ flux in thymocytes and, in combination with antibody against the CD3/TCR complex, promote thymocyte apoptosis and inhibit CD3-mediated proliferative responses of mature T lymphocytes.

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