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PE Anti-Mouse F4/80 Antibody [CI:A3-1] (AGEL0567)

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SKU AGEL0567
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone CI:A3-1
Conjugation PE
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Description

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PE Anti-Mouse F4/80 Antibody [CI:A3-1]

The Mouse F4/80 Monoclonal Antibody PE-Conjugated (Clone: CI:A3-1, AGEL0567) is a specialized tool for immunological research with a focus on macrophage detection and analysis. This antibody is specifically designed for identifying F4/80, a well-known marker for mature mouse macrophages, and is conjugated with PE for fluorescent detection applications.With its high specificity and sensitivity, this monoclonal antibody allows for precise recognition of F4/80 in various cell types and tissues, facilitating in-depth studies of macrophage populations and their roles in immune responses, inflammation, and tissue homeostasis.

This product is validated for flow cytometry applications, providing researchers with a reliable tool for investigating the dynamic functions of macrophages in different experimental settings.The F4/80 Monoclonal Antibody PE-Conjugated (Clone: CI:A3-1, AGEL0567) is essential for understanding the complex interactions between macrophages and the immune system, making it a valuable asset for studies in immunology, inflammation, and therapeutic development targeting macrophage-related diseases. Stay ahead in your research with this advanced tool for accurate and efficient macrophage detection and analysis.

Product Title:PE Anti-Mouse F4/80 Antibody [CI:A3-1]
SKU:AGEL0567
Size:25µg, 100µg
Clone No:CI:A3-1
Synonyms:Adhesion G protein-coupled receptor E1;Adgre1;Cell surface glycoprotein F4/80;EGF-like module receptor 1;Adgre1;Emr1; Gpf480;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q61549
Gene ID:13733
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:F4/80 is a 160 kD glycoprotein. It is characterized as a member of the epidermal growth factor (EGF)-transmembrane 7 (TM7) family. F4/80, also known as EMR1 or Ly71, has been widely used as a murine macrophage marker, which is expressed on the majority of tissue macrophages including peritoneal macrophages, macrophages in lung, gut, thymus and red pulp of spleen (but not on the macrophages located in T cell areas of the spleen, lymph node and Peyer's patch), Kuffer cells, Langerhans cells, and bone marrow stromal cells. F4/80 has also been shown on a subset of dendritic cells. The biological ligand of F4/80 has not been identified, but it has been reported that F4/80 is required for induction of CD8+ T cells-mediated peripheral tolerance.

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