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PerCP/Cyanine5.5 Anti-Mouse F4/80 Antibody [CI:A3-1] (AGEL0564)

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SKU AGEL0564
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone CI:A3-1
Conjugation PerCP/Cy5.5
€60 - €135
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Description

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PerCP/Cyanine5.5 Anti-Mouse F4/80 Antibody [CI:A3-1]

The Mouse F4/80 Monoclonal Antibody PerCP-Cyanine5.5 Conjugated (CI:A3-1) is a valuable tool for researchers investigating macrophage populations in various biological systems. This antibody, specifically targeting the F4/80 antigen, is ideal for flow cytometry applications, enabling the identification and analysis of macrophages in diverse tissues and experimental models.F4/80 is a well-established marker for mature macrophages and is widely used in immunology research to study the functions and distribution of these immune cells. The CI:A3-1 antibody, a monoclonal antibody conjugated to PerCP-Cyanine5.5, offers high sensitivity and specificity for detecting F4/80-expressing cells, providing researchers with a reliable tool for characterizing macrophage populations in both normal and disease states.

Understanding the role of macrophages in the immune response is essential for unraveling their involvement in various physiological and pathological processes, including inflammation, tissue repair, and immunity. The Mouse F4/80 Monoclonal Antibody PerCP-Cyanine5.5 Conjugated (CI:A3-1) facilitates such investigations by enabling precise detection and quantification of F4/80-positive macrophages, contributing to advancements in immunology, cancer research, and beyond.

Product Title:PerCP/Cyanine5.5 Anti-Mouse F4/80 Antibody [CI:A3-1]
SKU:AGEL0564
Size:50 Tests, 100 Tests, 200 Tests
Clone No:CI:A3-1
Synonyms:Adhesion G protein-coupled receptor E1;Adgre1;Cell surface glycoprotein F4/80;EGF-like module receptor 1;Adgre1;Emr1; Gpf480;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PerCP/Cyanine5.5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PerCP/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q61549
Gene ID:13733
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:F4/80 is a 160 kD glycoprotein. It is characterized as a member of the epidermal growth factor (EGF)-transmembrane 7 (TM7) family. F4/80, also known as EMR1 or Ly71, has been widely used as a murine macrophage marker, which is expressed on the majority of tissue macrophages including peritoneal macrophages, macrophages in lung, gut, thymus and red pulp of spleen (but not on the macrophages located in T cell areas of the spleen, lymph node and Peyer's patch), Kuffer cells, Langerhans cells, and bone marrow stromal cells. F4/80 has also been shown on a subset of dendritic cells. The biological ligand of F4/80 has not been identified, but it has been reported that F4/80 is required for induction of CD8+ T cells-mediated peripheral tolerance.

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