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GenieFluor 488 Anti-Mouse/Human CD11b Antibody [M1/70] (AGEL0311)

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SKU AGEL0311
Product Type Antibody
Antibody Type Monoclonal Antibody
Host Species Rat
Isotype IgG2b
Clone M1/70
Conjugation AF 488
Applications FC
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Description

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GenieFluor 488 Anti-Mouse/Human CD11b Antibody [M1/70]

The Mouse/Human CD11b Monoclonal Antibody (Alexa Fluor 488 Conjugated, M1/70) is a specialized antibody designed for research involving the CD11b cell surface molecule. This antibody, conjugated with Alexa Fluor 488 for fluorescent detection, is suitable for use in a variety of experimental techniques. CD11b, also known as integrin alpha M, is a crucial cell adhesion molecule involved in various immune responses, such as phagocytosis and cell migration. This antibody specifically targets the CD11b protein, allowing for precise detection and analysis in both mouse and human cell samples.

With its high reactivity and specificity, this antibody is validated for use in immunofluorescence, flow cytometry, and other molecular biology applications. Its unique ability to target CD11b makes it an essential tool for researchers studying immune function, inflammatory responses, and diseases related to aberrant immune cell activity. Unlock the potential of your research with the Mouse/Human CD11b Monoclonal Antibody (Alexa Fluor 488 Conjugated, M1/70) from Assay Genie.

Product Title:GenieFluor 488 Anti-Mouse/Human CD11b Antibody [M1/70]
SKU:AGEL0311
Size:50 Tests, 100 Tests, 200 Tests
Clone No:M1/70
Synonyms:Integrin alpha-M;Itgam;CD11 antigen-like family member B;CR-3 alpha chain;Leukocyte adhesion receptor MO1;CD11b;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor 488 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P05555 P11215
Gene ID:16409,3684
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

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