Description
system_update_altDatasheet
| Product Name: | Mouse IgG1 Isotype control monoclonal antibody (APC) |
| Product Code: | AGIM0490 |
| Size: | 100 µL |
| Reactivity: | Mouse |
| Clone: | 1F8 |
| Applications: | Flow Cytometry |
| Conjugate: | APC |
| Isotype: | IgG1 |
| Host Species: | Mouse |
| Storage: | Store at 4°C. Avoid prolonged exposure to light. |
| Uniprot: | Q9NV29 |
| Background: | The specificity of staining by monoclonal antibodies to target antigens should be verified by establishing the amount of non-specific antibody binding. In general, non-reactive immunoglobulin of the same isotype is included as a negative control for each specific monoclonal antibody used in a particular immunoassay. |
| UniProt Protein Function: | TMEM100: Plays a role during embryonic arterial endothelium differentiation and vascular morphogenesis through the ACVRL1 receptor-dependent signaling pathway upon stimulation by bone morphogenetic proteins, such as GDF2/BMP9 and BMP10. Up-regulated by GDF2/BMP9 and BMP10 (at protein level) Protein type: Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: 17q22 Cellular Component: perinuclear region of cytoplasm; endoplasmic reticulum; integral to membrane; plasma membrane; perikaryon Biological Process: BMP signaling pathway; Notch signaling pathway; positive regulation of endothelial cell differentiation; in utero embryonic development; protein kinase B signaling cascade; angiogenesis; vasculogenesis |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9NV29 |
| NCBI GenInfo Identifier: | 153792480 |
| NCBI Gene ID: | 55273 |
| NCBI Accession: | NP_001093110.1 |
| UniProt Secondary Accession: | Q9NV29,Q96FZ0, D3DTY7, I3L214 |
| UniProt Related Accession: | Q9NV29 |
| Molecular Weight: | 14,386 Da |
| NCBI Full Name: | transmembrane protein 100 |
| NCBI Synonym Full Names: | transmembrane protein 100 |
| NCBI Official Symbol: | TMEM100Â Â |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | transmembrane protein 100 |
| UniProt Protein Name: | Transmembrane protein 100 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Transmembrane protein |
| UniProt Gene Name: | TMEM100Â Â |
| UniProt Entry Name: | TM100_HUMAN |