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GenieFluor 488 Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5] (AGEL1487)

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SKU AGEL1487
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone RB6-8C5
Conjugation AF 488
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Description

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GenieFluor 488 Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5]

The Mouse LY-6G/LY-6C (GR-1) Monoclonal Antibody (AF488 Conjugated, RB6-8C5) is an essential tool for researchers investigating neutrophils and myeloid cells. This antibody, conjugated with AF488 for fluorescent detection, specifically targets the LY-6G and LY-6C antigens, also known as the GR-1 marker, commonly used to identify these cell populations. LY-6G/LY-6C (GR-1) is a critical marker for characterizing neutrophils, monocytes, and other myeloid cells in various experimental settings. The antibody's high specificity and sensitivity make it an excellent choice for flow cytometry, immunofluorescence, and other techniques aimed at studying the function and behavior of these immune cell subsets.

Understanding the role of LY-6G/LY-6C (GR-1) in immune response and inflammation is vital for unraveling mechanisms underlying disease pathogenesis and immune-mediated disorders. Researchers focusing on immunology, infection, inflammation, and cancer biology will benefit greatly from the accurate and reliable detection capabilities of this monoclonal antibody, enabling detailed analysis and profiling of cell populations in diverse biological contexts.

Product Title:GenieFluor 488 Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5]
SKU:AGEL1487
Size:25µg, 100µg
Clone No:RB6-8C5
Synonyms:Gr-1;Gr1;Ly-6G/Ly-6C;Ly6G/Ly6C;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor 488 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P35461 P0CW03
Gene ID:546644 ,17067
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Immature Myeloid Gr-1+ cells play a role in the development of antitumor immunity.

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