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APC Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5] (AGEL1481)

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SKU AGEL1481
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone RB6-8C5
Conjugation APC
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Description

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APC Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5]

The Mouse LY-6G/LY-6C (Gr-1) Monoclonal Antibody (APC-conjugated, clone RB6-8C5, Cat# AGL1481) is a versatile tool for research involving the identification and study of specific cell populations in murine models. This highly specific antibody targets the LY-6G/LY-6C (Gr-1) antigen, which is commonly used to identify granulocytes and monocytes in various biological samples.The monoclonal antibody, conjugated with APC, offers a reliable method for flow cytometry analysis, enabling precise and efficient detection of the LY-6G/LY-6C (Gr-1) antigen in complex mixtures of cells. Researchers can utilize this antibody to characterize immune cell subsets, investigate inflammatory responses, and explore the role of granulocytes and monocytes in various disease models.

The LY-6G/LY-6C (Gr-1) Monoclonal Antibody is a valuable tool for immunologists, cell biologists, and researchers working in fields such as immunology, inflammation, and cancer biology. Its high specificity and reproducibility make it an essential reagent for in vitro and in vivo studies aimed at elucidating the function and behavior of immune cells in different biological contexts. By utilizing this antibody, researchers can gain deeper insights into immune cell dynamics and their roles in health and disease.

Product Title:APC Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5]
SKU:AGEL1481
Size:25µg, 100µg
Clone No:RB6-8C5
Synonyms:Gr-1;Gr1;Ly-6G/Ly-6C;Ly6G/Ly6C;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:APC Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P35461 P0CW03
Gene ID:546644 ,17067
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Immature Myeloid Gr-1+ cells play a role in the development of antitumor immunity.

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