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PE/Cyanine7 Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5] (AGEL1484)

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SKU AGEL1484
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone RB6-8C5
Conjugation PE/Cy7
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Description

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PE/Cyanine7 Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5]

The Mouse Ly-6G/Ly-6C (Gr-1) Monoclonal Antibody, PE-Cyanine7 Conjugated (RB6-8C5) is a valuable tool for researchers studying immune cell populations in mice. This antibody is specifically designed to target the Ly-6G/Ly-6C (Gr-1) markers, commonly used to identify granulocytes and monocytes in flow cytometry and immunofluorescence experiments.The RB6-8C5 monoclonal antibody, conjugated with PE-Cyanine7, offers high specificity and sensitivity for detecting Ly-6G/Ly-6C (Gr-1) expression in various cell types. By binding to these cell surface markers, researchers can effectively analyze and characterize different immune cell populations, aiding in the investigation of inflammatory responses, infection, and immune-related diseases in mouse models.

This conjugated antibody is an essential tool for immunologists, oncologists, and researchers working in the fields of immunology, infectious diseases, and vaccine development. It allows for precise identification and quantification of Ly-6G/Ly-6C (Gr-1) expressing cells, enabling in-depth study of immune responses and immune cell dynamics in experimental settings.

Product Title:PE/Cyanine7 Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5]
SKU:AGEL1484
Size:25µg, 100µg
Clone No:RB6-8C5
Synonyms:Gr-1;Gr1;Ly-6G/Ly-6C;Ly6G/Ly6C;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE/Cyanine7 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P35461 P0CW03
Gene ID:546644 ,17067
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Immature Myeloid Gr-1+ cells play a role in the development of antitumor immunity.

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