GenieFluor 488 Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114]
The Mouse MHC II (I-A/I-E) Monoclonal Antibody (AF488-conjugated) (M5/114) is a specialized tool for researchers working with mouse models in immunology and related fields. This monoclonal antibody, clone M5/114, is conjugated with AF488 for convenient and sensitive detection in fluorescence-based assays. MHC II molecules play a vital role in antigen presentation to CD4+ T cells, initiating immune responses and regulating immunity. The specificity of this antibody for the I-A and I-E forms of MHC II makes it a valuable tool for studying antigen presentation pathways and immune recognition in mouse models.
This antibody is rigorously tested and validated for use in techniques such as flow cytometry, immunofluorescence, and immunohistochemistry, providing researchers with reliable results for their experiments. With its high reactivity and specificity, the Mouse MHC II (I-A/I-E) Monoclonal Antibody (AF488-conjugated) (M5/114) is a valuable asset for understanding the complex mechanisms of immune responses in mouse models.
Product Title:
GenieFluor 488 Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114]
SKU:
AGEL0507
Size:
25µg, 100µg
Clone No:
M5/114
Synonyms:
H2-Ab1/Eb1;Major histocompatibility protein class II beta chain;MHC class II H2-IA-beta-psi;I-E beta MHC class II;MHC class II;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
Genie Fluor 488 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
Genie Fluor488
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P14483 O78196
Gene ID:
14961,14969
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
These class II molecules are expressed on antigen presenting cells (including B cells) and a subset of T cells from H-2b,d,q,r bearing mice and are involved in antigen presentation to T cells expressing CD3/TCR and CD4 proteins.
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