The Mouse TCR Monoclonal Antibody (PE Conjugated) H57-597 (HB218) is a valuable tool for researchers studying T cell receptor (TCR) biology in mice. This antibody, conjugated to phycoerythrin (PE), specifically targets the TCR complex, a key component of T cell activation and function.The H57-597 (HB218) antibody is highly specific and shows strong reactivity in mouse samples, making it ideal for flow cytometry and immunofluorescence applications. It allows for the detection and analysis of TCR-expressing cells in various mouse tissues and cell populations, enabling researchers to investigate T cell responses in immunology, infectious diseases, and cancer immunotherapy.
Understanding the role of TCR signaling in immune responses is essential for developing therapies that target T cells for disease treatment. The H57-597 (HB218) antibody provides researchers with a reliable tool to delve deeper into T cell biology, paving the way for advancements in immunotherapy and disease treatment strategies.
Product Title:
PE Anti-Mouse TCRβ Antibody [H57-597 (HB218)]
SKU:
AGEL1548
Size:
25µg, 100µg
Clone No:
H57-597 (HB218)
Synonyms:
TCR-β chain; TCR-β; β-TCR;
Host Species:
Armenian Hamster
Reactivity:
Mouse
Application:
FCM
Isotype:
Armenian Hamster IgG
Isotype Control:
PE Armenian Hamster IgG Isotype Control[PIP]
Form:
Liquid
Conjugation:
PE
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Gene ID:
21577
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR-β is a member of the immunoglobulin superfamily and a component of the CD3/TCR complex (along with TCR-α). It is expressed on α/β TCR-bearing T cells and thymocytes. The CD3/TCR complex plays a key role in antigen recognition, signal transduction, and T cell activation.
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