The MRC2 Antibody (CAB9858) is a high-quality antibody developed for reliable detection and analysis of target proteins. This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease. RRID AB_2770423 Gene ID 9902 Swiss Prot Synonym CD280; UPARAP; CLEC13E; ENDO180; MRC2
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
MRC2 Antibody
SKU:
CAB9858
Size:
100μL, 20μL
Reactivity:
Human, Mouse
Clone Number:
-
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Tested Applications:
WBELISA
Recommended Dilution:
WB
1:500 - 1:2000
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
CD280, UPARAP, CLEC13E, ENDO180, MRC2
Positive Sample:
SH-SY5Y, HeLa, Mouse kidney
Cellular Localization:
Membrane, Single-Pass Type I Membrane Protein.
Calculated MW:
167kDa
Observed MW:
190kDa
This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease. RRID AB_2770423 Gene ID 9902 Swiss Prot Synonym CD280; UPARAP; CLEC13E; ENDO180; MRC2
Purification Method:
Affinity purification
Gene ID:
9902
RRID:
AB_2770423
Buffer Information:
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using MRC2 Rabbit pAb (CAB9858) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 10s.
