Description
MRPL9 Antibody (PACO10595)
The MRPL9 Monoclonal Antibody (PAC010595) is a valuable tool for researchers studying MRPL9, a mitochondrial ribosomal protein involved in protein synthesis. This antibody, developed using hybridoma technology, specifically targets MRPL9 in both human and mouse samples, making it suitable for a wide range of research applications.MRPL9 is a key player in the mitochondrial ribosomal machinery, essential for the translation of mitochondrial genes. Dysregulation of MRPL9 has been linked to various diseases, including cancer and neurological disorders, highlighting its importance in cellular function and health.
By using the MRPL9 antibody in experiments such as Western blotting and immunofluorescence, researchers can gain insights into the role of MRPL9 in mitochondrial function and disease pathology.Overall, the MRPL9 Monoclonal Antibody is a reliable tool for investigating the function and dysregulation of MRPL9 in various research areas, including cancer biology, neurology, and mitochondrial disorders. Its high specificity and reactivity make it a valuable asset for scientists aiming to unravel the molecular mechanisms underlying these conditions.
| Antibody Name: | MRPL9 Antibody (PACO10595) |
| Antibody SKU: | PACO10595 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human MRPL9 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | mitochondrial ribosomal protein L9;MRPL9;L9mt ; |
| UniProt Protein Function: | MRPL9: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found at 8q21.11. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Ribosomal; Mitochondrial; Translation Chromosomal Location of Human Ortholog: 1q21 Cellular Component: mitochondrial inner membrane; mitochondrion Molecular Function:protein binding Biological Process: translation |
| NCBI Summary: | This is a nuclear gene encoding a protein component of the 39S subunit of the mitochondrial ribosome. Alternative splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8. [provided by RefSeq, Jul 2014] |
| UniProt Code: | Q9BYD2 |
| NCBI GenInfo Identifier: | 209572671 |
| NCBI Gene ID: | 65005 |
| NCBI Accession: | Q9BYD2.2 |
| UniProt Secondary Accession: | Q9BYD2,Q5SZR2, Q9BSW8, B2RD99, |
| UniProt Related Accession: | Q9BYD2 |
| Molecular Weight: | 30,243 Da |
| NCBI Full Name: | 39S ribosomal protein L9, mitochondrial |
| NCBI Synonym Full Names: | mitochondrial ribosomal protein L9 |
| NCBI Official Symbol: | MRPL9Â Â |
| NCBI Official Synonym Symbols: | L9mt  |
| NCBI Protein Information: | 39S ribosomal protein L9, mitochondrial |
| UniProt Protein Name: | 39S ribosomal protein L9, mitochondrial |
| Protein Family: | 39S ribosomal protein |
| UniProt Gene Name: | MRPL9Â Â |
| UniProt Entry Name: | RM09_HUMAN |
