The MT-ND6 Monoclonal Antibody is a powerful tool for researchers studying mitochondrial biology and function. This antibody, produced by Assay Genie, specifically targets the MT-ND6 protein, a critical component of complex I in the electron transport chain. By targeting this protein, researchers can analyze mitochondrial function in various cell types and tissues.The MT-ND6 Monoclonal Antibody is highly specific to human samples and is validated for use in techniques such as Western blotting, immunofluorescence, and immunohistochemistry.
Its ability to detect and quantify MT-ND6 protein levels makes it an essential tool for investigating mitochondrial dysfunction in diseases such as cancer, neurodegenerative disorders, and metabolic diseases.Overall, the MT-ND6 Monoclonal Antibody offers researchers a valuable tool for understanding the role of mitochondrial function in health and disease. Its precision and reliability make it a key asset for studies aiming to elucidate the complex mechanisms of mitochondrial biology and its impact on cellular physiology.
Product Name:
MT-ND6 Monoclonal Antibody
SKU:
CAB21250
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 70-150 of human MT-ND6 (YP_003024037.1).
mitochondrial inner membrane, mitochondrial respiratory chain complex I
Calculated MW:
19kDa
Observed MW:
Refer to figures
Enables NADH dehydrogenase (ubiquinone) activity. Involved in mitochondrial electron transport, NADH to ubiquinone and mitochondrial respiratory chain complex I assembly. Predicted to be located in mitochondrial inner membrane. Implicated in Leber hereditary optic neuropathy; Leigh disease; and spinal muscular atrophy with lower extremity predominante 2B.
Purification Method:
Affinity purification
Gene ID:
4541
Clone Number:
ARC52554
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded human liver using MT-ND6 Rabbit mAb (CAB21250) at dilution of 1:200 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
