The MTAP Monoclonal Antibody (CAB22045) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced using a monoclonal antibody technology, offers high specificity and sensitivity for detecting MTAP protein in various biological samples.MTAP plays a crucial role in regulating cellular methionine metabolism and has been implicated in cancer progression and drug resistance. By targeting MTAP with this antibody, researchers can better understand its function and potential therapeutic implications in cancer treatment. The antibody is suitable for use in applications such as Western blotting, immunofluorescence, and immunohistochemistry, allowing for detailed analysis of MTAP expression in different cellular contexts.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
MTAP Monoclonal Antibody
SKU:
CAB22045
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC54717
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage pathway of both adenine and methionine. The encoded enzyme is deficient in many cancers. Multiple alternatively spliced transcript variants have been described for this gene.
Purification Method
Affinity purification
Gene ID
4507
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using MTAP Rabbit mAb (CAB22045) at1:2000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
