The MTMR12 Polyclonal Antibody (PACO10644) is a valuable tool for researchers studying MTMR12, a phosphatase enzyme involved in regulating cellular signaling pathways. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it an excellent choice for Western blot analysis. By targeting the MTMR12 protein, this antibody allows for precise detection and analysis across various cell types, making it ideal for investigations in cell signaling and disease mechanisms.MTMR12 is known to play a key role in processes such as autophagy, membrane trafficking, and cell growth regulation.
Dysregulation of MTMR12 has been linked to various diseases, including cancer, neurodegenerative disorders, and metabolic conditions. Therefore, understanding the functions of MTMR12 is essential for uncovering potential therapeutic targets and developing treatments for these conditions.By using the MTMR12 Polyclonal Antibody, researchers can gain valuable insights into the roles of MTMR12 in cellular processes and disease pathogenesis, ultimately advancing our knowledge of intracellular signaling mechanisms and contributing to the development of novel therapeutic strategies.
myotubularin related protein 12;MTMR12;3-PAP;PIP3AP ;
UniProt Protein Function:
MTMR12: Catalytically inactive phosphatase that plays a role as an adapter for the phosphatase myotubularin to regulate myotubularin intracellular location. Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Adaptor/scaffold; Protein phosphatase, tyrosine (non-receptor)Chromosomal Location of Human Ortholog: 5p13.3Cellular Component: cytoplasmMolecular Function: protein binding; phosphoric monoester hydrolase activityBiological Process: dephosphorylation
UniProt Protein Details:
NCBI Summary:
Phosphatidylinositide 3-kinase-derived membrane-anchored phosphatidylinositides, such as phosphatidylinositol 3-phosphate (PtdIns(3)P), regulate diverse cellular processes. The protein encoded by this gene functions as an adaptor subunit in a complex with an active PtdIns(3)P 3-phosphatase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
